{"topic_id":"evidence_exotic_fish_clinical","category":"evidence","context":"---\ntopic_id: evidence_exotic_fish_clinical\ncategory: evidence\ntitle: \"Evidence cluster — Aquarium fish (teleost fish) clinical cases (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-08-01\"\nsource_file: pdf-raw/evidence/europepmc_fish_clinical_2026-08-01.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 5020\nverification:\n  method: substring_match\n  claims: 5\n  passed: 5\n  date: 2026-08-01\nsource_document: \"Peer-reviewed Aquarium fish clinical-case literature (Europe PMC, first-hand abstracts)\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — Aquarium fish (teleost fish) clinical cases (peer-reviewed, Europe PMC)\"\n  url: \"https://www.ebi.ac.uk/europepmc/\"\n  retrieved: \"2026-08-01\"\n  doc_type: \"first-hand abstracts (Europe PMC REST)\"\n  needs_review: false\nlicense: cc_by\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: Aquarium fish (teleost fish) clinical cases\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-08-01.\nQueries covered clinical case reports and case series for teleost fish.\nThe cluster returns **5** representative clinical cases with abstracts below. Abstract text is verbatim from source; each case is traceable by PMID.\n\n## Studies\n- **PMID 42188959 (2026, Veterinary sciences)** — Systemic Granulomatous Mycobacteriosis in Orbiculate Batfish (&lt;i&gt;Platax orbicularis&lt;/i&gt;) Associated with &lt;i&gt;Mycobacterium marinum&lt;/i&gt;-like Organism in an Aquarium in South Korea.. Abstract (opening): In this report, we describe systemic granulomatous mycobacteriosis in an orbiculate batfish from an aquarium in South Korea. Gross examination of the deceased fish showed multifocal nodular lesions in multiple internal organs including the gills, spleen, and kidney. Histopathological analysis demonstrated severe chronic systemic granulomatous inflammation, and Ziehl-Neelsen staining highlighted abundant intralesional acid-fast bacilli. Molecular analysis based on partial sequencing of the 16S ribosomal RNA (rRNA) and heat shock protein 65 (<i>hsp65</i>) genes showed that the detected organism was most closely related to <i>Mycobacterium marinum.</i> Because the molecular analysis was performed using partial sequences obtained from formalin-fixed, paraffin-embedded tissues, definitive species-level identification was not possible. This case represents systemic granulomatous mycobacteriosis associated with a <i>Mycobacterium marinum</i>-like organism in orbiculate batfish in an aquarium in South Korea and emphasizes the need for continuous disease surveillance and improved diagnostic awareness of non-tuberculous mycobacterial infections in ornamental and public aquarium fish.\n  Source: https://pubmed.ncbi.nlm.nih.gov/42188959/\n- **PMID 41189540 (2026, Molecular ecology resources)** — eDNAmap: A Metabarcoding Web Tool for Comparing Marine Biodiversity, With Special Reference to Teleost Fish.. Abstract (opening): Marine environmental DNA (eDNA) metabarcoding data are beginning to accumulate, even for remote and poorly studied areas, such as marine environments. These data enable us to identify distributions of target organisms and then to compare biological compositions between different marine areas. However, there is no platform to effectively utilise and accumulate these data. In this study, we developed eDNAmap, a web-based platform designed to analyse and store marine eDNA metabarcoding data. By uploading species or sequence composition data with location information, eDNAmap users can automatically (1) plot sampling locations on a map, (2) generate a heatmap to evaluate potential batch effects arising from methodological differences and (3) perform nonmetric multidimensional scaling and cluster analyses using similarity indices. Furthermore, users can specify scientific names to display species distributions and upload species lists to assess species compositions of the target sea area. As an example, fish sequence composition data obtained from 55 stations around the Watase line-believed to exist along a geographic canyon known as the Tokara Gap-were used to verify its existence using eDNAmap. The platform includes a database primarily consisting of teleost fish data from the Northwestern Pacific, which users can analyse similarly to their own uploads. Although originally designed for fish, eDNAmap is flexible enough to handle data from other marine organisms. Analysing multiple taxa enables the detection of concordant biogeographic patterns across different groups, which can strengthen ecological interpretations and lay the groundwork for identifying environmental drivers shaping community structures. eDNAmap is available at https://github.com/jun-inoue/eDNAmap.\n  Source: https://pubmed.ncbi.nlm.nih.gov/41189540/\n- **PMID 42262143 (2026, Ecological applications : a publication of the Ecological Society of America)** — Evaluating species at risk in data-limited fisheries: A productivity-susceptibility analysis for marine aquarium fish.. Abstract (opening): The marine aquarium trade (MAT) is a significant global industry harvesting millions of wild-caught, live coral reef fishes for public and private aquaria markets in the United States and Europe annually, while supporting fisher livelihoods in the Indo-Pacific. This diverse and species-rich trade is considered data-limited, creating barriers to quantifying the current and future socio-ecological sustainability of the fishery. We present a revised and expanded productivity-susceptibility analysis (PSA) that serves as a holistic risk assessment to estimate the vulnerability of marine aquarium fish to overfishing. Our global analysis includes 306 species that are actively in trade. Improvements to the PSA framework from previous research including novel susceptibility factors, methods to overcome missing data for individual species factors, and assessing a large, diverse group of marine fish under a single, targeted assessment framework. Our results show that an overwhelming 81.4% of species evaluated fall into the least or moderately vulnerable classification, while the remaining species (n = 57) have higher vulnerability scores designating them as high priority for localized assessment and management initiatives. Most teleost fish in the trade are considered sustainable, while eels and elasmobranchs have the highest vulnerability scores. A comparative case study between our PSA and the popular FishBase vulnerability tool illustrates how the latter can be ill-suited to handle the data limitations common to nonfood fishes. Our study demonstrates how the PSA is a robust, data-limited fishery assessment to prioritize species in the MAT for further assessment, monitoring, and management.\n  Source: https://pubmed.ncbi.nlm.nih.gov/42262143/\n- **PMID 41229695 (2025, Ecology and evolution)** — Extremely Small Clutch Size and Juvenile Survival in a Social Cichlid of an African Great Lake.. Abstract (opening): <i>Neolamprologus buescheri</i>, a cooperatively breeding cichlid fish endemic to Lake Tanganyika, exhibits one of the slowest life histories documented among teleost fish. With remarkably small clutch sizes ranging from one to seven eggs (median = 3) and exceptionally high juvenile survival rates of over 50% within two months, this species deviates significantly from typical fish reproductive patterns. Its slow somatic growth, prolonged parental care, and occupation of deep-water habitats place it at the extreme end of the fast-slow life-history continuum among fish.\n  Source: https://pubmed.ncbi.nlm.nih.gov/41229695/\n- **PMID 42005339 (2025, Veterinary evidence)** — Do opioids provide adequate analgesia for surgical coeliotomy in teleost fish?. Abstract (opening): <h4>Pico question</h4>For teleost fish undergoing surgical coeliotomy, do intramuscular exogenous opioids reduce perioperative pain, compared with no analgesia?<h4>Clinical bottom line</h4><h4>Category of research</h4>Treatment.<h4>Number and type of study designs reviewed</h4>Four studies were critically reviewed. All were randomised controlled trials, 2 with a parallel group design, and 2 with a factorial crossover group design.<h4>Strength of evidence</h4>Moderate.<h4>Outcomes reported</h4>The studies produced contradicting results regarding the analgesic efficacy of opioids perioperatively, with some evidence of pain alleviation when assessing behavioural parameters, but not when assessing clinical pathology or quantitative cardioventilatory data.<h4>Conclusion</h4>Perioperative use of opioids for teleost fish undergoing invasive surgical procedures may reduce behavioural changes associated with pain compared with no analgesia, but there is insufficient evidence to determine if they provide adequate pain relief based on the study methodologies.\n  Source: https://pubmed.ncbi.nlm.nih.gov/42005339/\n\nSource text: `pdf-raw/evidence/europepmc_fish_clinical_2026-08-01.txt` (Europe PMC first-hand abstracts, pulled 2026-08-01).\n\n## License & attribution\n\nSource abstracts / records are Open Access under Creative Commons. Each referenced\nstudy is reproduced with attribution under its specific CC license (CC BY / CC BY-NC /\nCC BY-NC-ND); the exact license variant for each reference is stated on its Europe PMC /\nPMC record. Original records:\n- https://pubmed.ncbi.nlm.nih.gov/42188959/\n- https://pubmed.ncbi.nlm.nih.gov/41189540/\n- https://pubmed.ncbi.nlm.nih.gov/42262143/\n- https://pubmed.ncbi.nlm.nih.gov/41229695/\n- https://pubmed.ncbi.nlm.nih.gov/42005339/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 42256938 — human case (hypokalemic periodic paralysis in a woman), not fish\nPMID 42182033 — Chilean salmon aquaculture antimicrobial-resistance/sustainability production-system review, not a fish clinical subject\nPMID 41878422 — human cytokine-signaling (CISH/SOCS) immunology review, not fish\nPMID 40001054 — Aeromonas AMR/epidemiology review of humans + aquatic animals, not a fish clinical study\nPMID 40519665 — human fetal sirenomelia case, not fish\nPMID 40665361 — human vitamin D allergy case, not fish\nPMID 41404115 — Ichthyophthirius in wild AMPHIBIANS, fish parasite only incidental, not a fish subject\n","sources":["Europe PMC — Evidence cluster — Aquarium fish (teleost fish) clinical cases (peer-reviewed, Europe PMC) (retrieved 2026-08-01)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — Aquarium fish (teleost fish) clinical cases (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/42188959/","retrieved":"2026-08-01","ref":"PMID 42188959","doc_type":"official PDF","source_document":"Peer-reviewed Aquarium fish clinical-case literature (Europe PMC, first-hand abstracts)","verification_file":"pdf-raw/evidence/europepmc_fish_clinical_2026-08-01.txt"},"source_document":"Peer-reviewed Aquarium fish clinical-case literature (Europe PMC, first-hand abstracts)","source_file":"pdf-raw/evidence/europepmc_fish_clinical_2026-08-01.txt","trust":{"authority_tier":"T2","fidelity":"verbatim","license":"cc_by","display_grade":"A"},"tokens_estimated":600,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}