{"topic_id":"evidence_exotic_leopard_gecko_metabolic_bone_disease","category":"evidence","context":"---\ntopic_id: evidence_exotic_leopard_gecko_metabolic_bone_disease\ncategory: evidence\ntitle: \"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-08-01\"\nsource_file: pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 4400\nverification:\n  method: paraphrase\n  claims: 6\n  passed: 6\n  date: 2026-08-01\nsource_document: \"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)\"\n  url: \"https://www.ebi.ac.uk/europepmc/\"\n  retrieved: \"2026-08-01\"\n  doc_type: \"first-hand abstracts (Europe PMC REST)\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: Eublepharis macularius metabolic bone disease\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-08-01.\nQueries covered metabolic bone disease for Eublepharis macularius.\nThe cluster returns **6** representative studies with abstracts below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n\n- **PMID 41514721 (2025, Animals : an open access journal from MDPI)** — &lt;i&gt;Cryptosporidium varanii&lt;/i&gt; Infection in Captive Leopard Gecko (&lt;i&gt;Eublepharis macularius&lt;/i&gt;) and Its Association with Wasting Syndrome in Thailand.. Abstract (opening): Cryptosporidiosis is a globally important protozoan disease that causes severe gastrointestinal illness in immunocompromised humans and animals and has been associated with chronic wasting and death in reptiles. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/41514721/\n- **PMID 41600686 (2025, Veterinary sciences)** — Biochemical and Hepatic Determinants of Reproductive Failure in Reptiles: A Review of Dystocia Pathophysiology and Management.. Abstract (opening): Dystocia represents a multifactorial and clinically significant reproductive disorder affecting a broad spectrum of reptilian species. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/41600686/\n- **PMID 32950659 (2020, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology)** — *[Paraphrased derived summary — non-Open-Access source.]* The nocturnal leopard gecko (Eublepharis macularius) uses UVB radiation for vitamin D3 synthesis; vitamin D is an important regulator of calcium and phosphorus homeostasis. (Source excerpt truncated at abstract opening.)\n  Source: https://pubmed.ncbi.nlm.nih.gov/32950659/\n- **PMID 38997984 (2024, Animals : an open access journal from MDPI)** — Assessment of Animal Welfare at an Exotic Animal Fair in Poland: A Focus on the Quality of Exhibition Containers for Reptiles and Amphibians.. Abstract (opening): Given the growing number of events involving exotic animals, it is crucial to prioritize the well-being of the animals involved. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/38997984/\n- **PMID 41180164 (2025, Animal welfare (South Mimms, England))** — Laying the groundwork for reptile welfare assessment in zoos and private keeping: A literature-based proposal.. Abstract (opening): With the increasing number and diversity of reptile species kept in zoological facilities and households, their welfare in captivity warrants structured and consistent evaluation. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/41180164/\n- **PMID 32580733 (2020, Journal of ethnobiology and ethnomedicine)** — The use of fish and herptiles in traditional folk therapies in three districts of Chenab riverine area in Punjab, Pakistan.. Abstract (opening): <h4>Background</h4>Like botanical taxa, various species of animals are also used in traditional and modern health care systems. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/32580733/\n\n---\n\n**Source:** `pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt` · https://www.ebi.ac.uk/europepmc/\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/41514721/\n- https://pubmed.ncbi.nlm.nih.gov/41600686/\n- https://pubmed.ncbi.nlm.nih.gov/32950659/\n- https://pubmed.ncbi.nlm.nih.gov/38997984/\n- https://pubmed.ncbi.nlm.nih.gov/41180164/\n- https://pubmed.ncbi.nlm.nih.gov/32580733/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 40987466 — leopard gecko iridophoroma (neoplasm), not MBD — entry labeled off-topic mis-clustered\nPMID 41150105 — subject is blue-tongued skink (Tiliqua scincoides), a different species, not leopard gecko\n","sources":["Europe PMC — Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC) (retrieved 2026-08-01)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/41514721/","retrieved":"2026-08-01","ref":"PMID 41514721","doc_type":"official PDF","source_document":"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)","verification_file":"pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt"},"source_document":"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)","source_file":"pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":830,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}