{"topic_id":"exotic_tox_amphibian_metals","category":"exotic-pet-toxicology","context":"---\ntopic_id: exotic_tox_amphibian_metals\ncategory: exotic-pet-toxicology\ntitle: \"Metal (Cu, Cd, Zn, Ni, Pb) contaminant toxicity in amphibian tadpoles — environmental hazard\"\nlang: en\nsource: \"First-hand veterinary toxicology reference, saved to source_file; every claim is a C1 byte-substring of it. Deepened 2026-08-01.\"\nsource_file: pdf-raw/exotic-toxicology/amphibian_metals.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 441\nverification:\n  method: substring_match\n  claims: 10\n  passed: 10\n  date: 2026-08-01\nrecovered: false\npath: exotic-pet-toxicology/exotic_tox_amphibian_metals/01_exotic_tox_amphibian_metals.md\nsource_document: \"Silberschmidt Freitas J, Costa RN (2026) Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles. Ecotoxicology. PMC13282347 / PMID 42319528. SpringerOpen, CC BY 4.0.\"\ncitation:\n  authority: \"Silberschmidt Freitas J, Costa RN (2026) Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles. Ecotoxicology. PMC13282347 / PMID 42319528. SpringerOpen, CC BY 4.0.\"\n  title: \"Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles\"\n  url: \"https://pmc.ncbi.nlm.nih.gov/articles/PMC13282347/\"\n  retrieved: \"2026-08-01\"\n  ref: \"\"\n  doc_type: \"open-access journal article\"\n  needs_review: false\nlicense: cc_by\ncopyright_note: 'Reclassified from mislabeled \"Merck Veterinary Manual\" (source_file is the open-access SpringerOpen article PMC13282347, CC BY 4.0). Verbatim reproduction with attribution permitted per COPYRIGHT_POLICY §2.'\nauthority_tier: T2\nauthority_tier_basis: \"manual:peer-reviewed OA journal article (PMC13282347, Ecotoxicology, CC BY 4.0)\"\nauthority_tier_date: 2026-08-04\n---\n\n# Metal (Cu, Cd, Zn, Ni, Pb) contaminant toxicity in amphibian tadpoles — environmental hazard\n\nThe text below is reproduced verbatim from the first-hand source.\n\n## Claims (verified C1 substrings of source_file)\n\n- `To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Abstract\nAmphibians are highly vulnerable to environmental pollutants, especially during the larval stage, when temperature fluctuations in ephemeral ponds can interact with metals and alter their toxicity, a scenario that may be intensified by ongoing climate change.`\n- `This study investigated the toxicity of five metals on tadpoles of Rhinella diptycha and Leptodactylus fuscus, across two different temperatures (28 and 34 °C).`\n- `Species sensitivity distribution (SSD) curves were then constructed for each metal using LC50 data for both tropical species, together with those from the literature on other tadpole and standard fish species.`\n- `Toxicity ranking followed Cu > Cd > Zn > Pb > Ni in L.`\n- `In almost all cases, increased temperature enhanced metal toxicity in a dose-dependent effect.`\n- `fuscus as among the most sensitive species to metals.`\n- `Our findings show that metal toxicity can be amplified at higher temperatures, reinforcing the importance of accounting for temperature effects when establishing safe environmental concentrations of potential contaminants, particularly for species inhabiting warmer areas.`\n- `Metals are naturally occurring elements in the environment that can be found in several compartments, including aquatic ecosystems.`\n- `At low concentrations, metals such as iron (Fe), copper (Cu), and manganese (Mn) play beneficial roles for most organisms, as they are essential for various biochemical and physiological processes.`\n- `However, several anthropogenic activities, such as agriculture, mining, and industrial processes, can increase metal concentrations in natural systems, making them some of the most widespread contaminants on the planet (Aigberua et al.`\n\n---\n\n**Source:** `pdf-raw/exotic-toxicology/amphibian_metals.txt` · https://pmc.ncbi.nlm.nih.gov/articles/PMC13282347/\n","sources":["exotic-pet-toxicology — Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles (retrieved 2026-08-01)"],"source":{"authority":"exotic-pet-toxicology","title":"Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13282347/","retrieved":"2026-08-01","ref":"","doc_type":"official PDF","source_document":"Silberschmidt Freitas J, Costa RN (2026) Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles. Ecotoxicology. PMC13282347 / PMID 42319528. SpringerOpen, CC BY 4.0.","verification_file":"pdf-raw/exotic-toxicology/amphibian_metals.txt"},"source_document":"Silberschmidt Freitas J, Costa RN (2026) Acute toxicity of metals in Rhinella diptycha and Leptodactylus fuscus at different temperatures: a perspective for tropical tadpoles. Ecotoxicology. PMC13282347 / PMID 42319528. SpringerOpen, CC BY 4.0.","source_file":"pdf-raw/exotic-toxicology/amphibian_metals.txt","trust":{"authority_tier":"T2","fidelity":"verbatim","license":"cc_by","display_grade":"A"},"tokens_estimated":646,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}