proin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-08-16. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. "proin" is a name as filed in the drug active-ingredient field of these reports (may be a generic ingredient or a product/brand name as reported).
Total reports
proin: 267
Reports by species (top entries)
- Dog 264
- Cat 2
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 44
- Urinary incontinence 38
- Lethargy (see also Central nervous system depression in Neurological) 34
- Death by euthanasia 33
- Polydipsia 32
- Polyuria 27
- Ataxia 26
- Not eating 25
- Diarrhoea 23
- Seizure NOS 23
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-08-16_b1.json (openFDA animalandveterinary/event.json, pulled 2026-08-16).