Bengal — Coat colour and pattern, charcoal, ASIP-related (hereditary; OMIA-verified breed predisposition)

--- license: permission_granted topic_id: companion_breed_health_bengal_omia4955_cat category: companion-breed-health title: "Bengal — Coat colour and pattern, charcoal, ASIP-related (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/bengal_omia4955_4955.txt date_parsed: 2026-08-02 tokens_estimated: 213 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_bengal_omia4955_cat/01_companion_breed_health_bengal_omia4955_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Bengal — Coat colour and pattern, charcoal, ASIP-related (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA002549/9685/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Bengal — Coat colour and pattern, charcoal, ASIP-related (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

• Breed: Bengal (Cat)
• Disorder:
• Mode of inheritance: Autosomal incomplete dominant
• Summary: Gershony et al. (2014): The Bengal cat breed consists of hybrid animals originally developed from crosses between the domestic cat (Felis silvestris catus) and the Asian leopard cat (Prionailurus bengalensis) ... . An unusual pelage type involving a darker face ‘mask’ and a dark dorsal stripe, commonly referred to as a ‘cape’, is unique to the breed. This ‘charcoal’ pattern does not produce a fully melanistic cat (see a href=../../../../../../OMIA000201/9685/OMIA:000201-9685/a : Coat colour, agouti in Felis catus) but bestows darker and more extended markings ... , suggesting unusual interactions between melanism and patterning genes in the hybrid cats.
• Defect: no

Associated gene(s)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• Gene: Entrez Gene ID 492297 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
• OMIA molecular-genetics note: By sequencing a prime comparative candidate locus (ASIP) in Bengal cats, Asian leopard cats and domestic cats, Gershony et al. (2014) showed that the charcoal coat colouration/pattern in Bengal cats is strongly associated with compound heterozygosity for an ASIP haplotype from the euptilura form of Asian leopard cat (called A^Pbe) and the feline non-agouti allele a (ASIP:c.123-124del, omia.variant…

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• 2003. Molecular genetics and evolution of melanism in the cat family. Current Biology — PubMed:PMID12620197 — OMIA Phene_Article / Article
• 2014. Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. Anim Genet — PubMed:PMID25143047 | DOI:10.1111/age.12206 — OMIA Phene_Article / Article
• 2024. Ancestry dynamics and trait selection in a designer cat breed. Curr Biol — PubMed:PMID38531359 | DOI:10.1016/j.cub.2024.02.075 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• OMIM:600201 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
• OMIM:611742 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."