Rabbit (Oryctolagus cuniculus) — Adrenoleukodystrophy, ABCD1-related (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

Species: Rabbit (Oryctolagus cuniculus)
Disorder: Adrenoleukodystrophy, ABCD1-related
Summary: Zhou et al. (2024) created a rabit model for X-linked adrenoleukodystrophy using CRISPR/Cas9 technology to knock out ABCD1  and evaluated rAAV9-based gene therapy in these knockout rabbits. This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Associated gene(s)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

Gene: Entrez Gene ID 398299010 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

2025. Development of a rabbit model for adrenoleukodystrophy: A pilot study on gene therapy using rAAV9. Mol Ther Nucleic Acids — PubMed:PMID40027885 | DOI:10.1016/j.omtn.2025.102469 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

OMIM:300371 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
OMIM:300100 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Rabbit (Oryctolagus cuniculus) — Adrenoleukodystrophy, ABCD1-related (hereditary; OMIA-verified species predisposition)