Rabbit (Oryctolagus cuniculus) — Short QT syndrome, KCNH2-related (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Rabbit (Oryctolagus cuniculus)Disorder: Short QT syndrome, KCNH2-relatedSummary: This phene includes references to studies involving genetically modified organisms (GMO).
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: ERG (Entrez Gene ID 388912484) — OMIA Phene_Gene / GeneSynonym
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2022. Transgenic rabbit models for cardiac disease research. Br J Pharmacol — PubMed:PMID33822374 | DOI:10.1111/bph.15484 — OMIA Phene_Article / Article
- 2019. Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. Eur Heart J — PubMed:PMID30496390 | DOI:10.1093/eurheartj/ehy761 — OMIA Phene_Article / Article
- 2024. Beneficial normalization of cardiac repolarization by carnitine in transgenic SQT1 rabbit models. Cardiovasc Res — PubMed:PMID39018021 | DOI:10.1093/cvr/cvae149 — OMIA Phene_Article / Article
- 2025. AAV9-mediated KCNH2 suppression-replacement gene therapy in a transgenic rabbit model of type 1 short QT syndrome. Eur Heart J — PubMed:PMID40884219 | DOI:10.1093/eurheartj/ehaf660 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:609620 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:152427 (type: gene) — OMIA Group_OMIM (via OMIA_ID)