Cat (Felis catus) — Von Willebrand disease III (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Cat (Felis catus)Disorder: Von Willebrand disease IIIClin feat: vWD is rarely recognized in cats (Thomas 1996). French et al. (1987) diagnosed von Willebrand disease in a 9-year-old male Himalayan cat. The cat presented with persistent oral bleeding after routine dental extraction. Haematuria (blood in the urine), petechia, melena (black stools due to gastrointestinal bleeding) were also observed. Laboratory testing identified disseminated intravascular coagulation (thrombocytopenia, prolonged activated partial thromboplastin time, and increased fibrin degradation products) and recurring iron-deficiency anemia. Coagulation factor assays revealed low factor VIII coagulant activity and undetectable factor VIII-related antigen. The cat initially recovered after treatment but showed spontaneous gingival bleeding 8 month later. No history of abnormal bleeding existed for the cat's sire or dam.
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1996. Von Willebrand's disease in the dog and cat. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article
- 1987. A bleeding disorder (von Willebrand's disease) in a Himalayan cat. J Am Vet Med Assoc — PubMed:PMID3104251 — OMIA Phene_Article / Article
- 2012. Diagnostic approach to small animal bleeding disorders. Top Companion Anim Med — PubMed:PMID23031459 | DOI:10.1053/j.tcam.2012.07.004 — OMIA Phene_Article / Article
- 2023. Clinical assessment of primary hemostasis: A review. Top Companion Anim Med — PubMed:PMID37673175 | DOI:10.1016/j.tcam.2023.100818 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:277480 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:613160 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1996. Von Willebrand's disease in the dog and cat. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article
- 1987. A bleeding disorder (von Willebrand's disease) in a Himalayan cat. J Am Vet Med Assoc — PubMed:PMID3104251 — OMIA Phene_Article / Article
- 2012. Diagnostic approach to small animal bleeding disorders. Top Companion Anim Med — PubMed:PMID23031459 | DOI:10.1053/j.tcam.2012.07.004 — OMIA Phene_Article / Article
- 2023. Clinical assessment of primary hemostasis: A review. Top Companion Anim Med — PubMed:PMID37673175 | DOI:10.1016/j.tcam.2023.100818 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:277480 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:613160 (type: gene) — OMIA Group_OMIM (via OMIA_ID)