English Springer Spaniel — Factor XI deficiency (hereditary; OMIA-verified breed predisposition)

companion_breed_health_english_springer_spaniel_omia650_dog

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English Springer Spaniel — Factor XI deficiency (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

Breed: English Springer Spaniel (Dog)
Disorder:
Mode of inheritance: Autosomal
`Clin feat: Congenital Factor XI deficiency is characterised by abnormal haemostasis and excessive bleeding, usually following trauma or surgery. Clinical signs of abnormal haemostasis and excessive bleeding include bruising, epistaxis, and menorrhagia (Fogh and Fogh, 1988). Affected dogs have significantly decreased Factor XI activity levels (less than 10%), heterozygous/carrier dogs have decreased Factor XI activity levels, (25-50%) but appear to be asymptomatic (Fogh and Fogh, 1988).

Sources

English Springer Spaniel — Factor XI deficiency (hereditary; OMIA-verified breed predisposition)

Source document: OMIA — Online Mendelian Inheritance in Animals (University of Sydney)

OMIA — Online Mendelian Inheritance in Animals (University of Sydney)

OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70

retrieved 2026-08-02

Verification file: pdf-raw/breed-health/english_springer_spaniel_omia650_650.txt

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