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Dog (Canis lupus familiaris) — Hepatitis, chronic active (hereditary; OMIA-verified species predisposition)

companion_species_health_hepatitis_chronic_active_dog

companion-species-health 901 tok en 2026-08-24

Dog (Canis lupus familiaris) — Hepatitis, chronic active (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Species: Dog (Canis lupus familiaris)
  • Disorder: Hepatitis, chronic active
  • Summary: Chronic active hepatitis is one of the common causes of hepatic encephalopathy. In reviewing the published literature on dogs, Rothuizen et al. (1993) concluded that chronic active hepatitis is a "sex-linked disorder of females", most likely due to an immune defect.

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1993. Portosystemic hepatic encephalopathy related with congenital and acquired hepatopathies in the dog. Advances in Veterinary Science and Comparative Medicine — PubMed:PMID8273522 — OMIA Phene_Article / Article
  • 1985. Chronic active hepatitis in 26 Doberman Pinchers. Journal of the American Veterinary Medical Association — PubMed:PMID4086350 — OMIA Phene_Article / Article
  • 1982. Chronic active hepatitis in Doberman Pinchers. Journal of the American Veterinary Medical Association — PubMed:PMID7096184 — OMIA Phene_Article / Article
  • 1988. Chronic active hepatitis with cirrhosis in the Doberman Pincher. Veterinary Quarterly — PubMed:PMID3413974 — OMIA Phene_Article / Article
  • 1995. Chronic hepatitis in dogs. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article
  • 2012. DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel. PLoS One — PubMed:PMID22870335 | DOI:10.1371/journal.pone.0042584 — OMIA Phene_Article / Article
  • 2025. A case of canine hepatitis with hepatocellular attack by non-neoplastic perforin-laden lymphocytes. Vet Sci — PubMed:PMID40266952 | DOI:10.3390/vetsci12030211 — OMIA Phene_Article / Article

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1993. Portosystemic hepatic encephalopathy related with congenital and acquired hepatopathies in the dog. Advances in Veterinary Science and Comparative Medicine — PubMed:PMID8273522 — OMIA Phene_Article / Article
  • 1985. Chronic active hepatitis in 26 Doberman Pinchers. Journal of the American Veterinary Medical Association — PubMed:PMID4086350 — OMIA Phene_Article / Article
  • 1982. Chronic active hepatitis in Doberman Pinchers. Journal of the American Veterinary Medical Association — PubMed:PMID7096184 — OMIA Phene_Article / Article
  • 1988. Chronic active hepatitis with cirrhosis in the Doberman Pincher. Veterinary Quarterly — PubMed:PMID3413974 — OMIA Phene_Article / Article
  • 1995. Chronic hepatitis in dogs. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article
  • 2012. DLA class II alleles and haplotypes are associated with risk for and protection from chronic hepatitis in the English Springer spaniel. PLoS One — PubMed:PMID22870335 | DOI:10.1371/journal.pone.0042584 — OMIA Phene_Article / Article
  • 2025. A case of canine hepatitis with hepatocellular attack by non-neoplastic perforin-laden lymphocytes. Vet Sci — PubMed:PMID40266952 | DOI:10.3390/vetsci12030211 — OMIA Phene_Article / Article

Sources

Dog (Canis lupus familiaris) — Hepatitis, chronic active (hereditary; OMIA-verified species predisposition)
Source document: OMIA — Online Mendelian Inheritance in Animals (University of Sydney)
OMIA — Online Mendelian Inheritance in Animals (University of Sydney)OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70retrieved 2026-08-24

Verification file: pdf-raw/species-health/dog_hepatitis_chronic_active_1.txt