Rabbit (Oryctolagus cuniculus) — Microcephaly, YIPF5-related (hereditary; OMIA-verified species predisposition)

companion_species_health_microcephaly_yipf5_related_rabbit

Rabbit (Oryctolagus cuniculus) — Microcephaly, YIPF5-related (hereditary; OMIA-verified species predisposition)

Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

Species: Rabbit (Oryctolagus cuniculus)
Disorder: Microcephaly, YIPF5-related
Summary: Liu et al. (2023) "constructed a rabbit PMCPH [primary microcephaly] model harboring YIPF5 (p.W218R) mutation using SpRY-ABEmax mediated base substitution, which precisely recapitulated the typical symptoms of human PMCPH." This study involves genetically modified organisms (GMO).

Associated gene(s)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

Gene: Entrez Gene ID 389123594 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

2023. YIPF5 (p.W218R) mutation induced primary microcephaly in rabbits. Neurobiol Dis — PubMed:PMID37142085 | DOI:10.1016/j.nbd.2023.106135 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

OMIM:611483 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
OMIM:619278 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

Sources

Rabbit (Oryctolagus cuniculus) — Microcephaly, YIPF5-related (hereditary; OMIA-verified species predisposition)

Source document: OMIA — Online Mendelian Inheritance in Animals (University of Sydney)

OMIA — Online Mendelian Inheritance in Animals (University of Sydney)

OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70

retrieved 2026-08-24

Verification file: pdf-raw/species-health/rabbit_microcephaly_yipf5_related_5318.txt

Machine access

AI agents: this page mirrors GET /api/v1/llm_context?topic=companion_species_health_microcephaly_yipf5_related_rabbit (max 500 tokens, whitelisted). Rate limit 120 req/min for recognized AI crawlers.

Raw JSON ↗ llm.txt OpenAPI