Hamster — Woodhouse-Sakati syndrome (hereditary; OMIA-verified species predisposition)
Source: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Species: Mesocricetus auratus / Phodopus spp. (hamster)Disorder:Summary: Ma et al. (2024): "As a model to explore the role of Dcaf17 in the male reproductive system, we created Dcaf17-deficient male golden hamsters using CRISPR-Cas9 technology, the results of which demonstrate that deletion of Dcaf17 led to abnormal spermatogenesis and infertility." This study involves gene edited or genetically modified organisms (GMO).Defect: yes
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 398298945 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2024. Single-cell RNA Sequencing reveals the important role of Dcaf17 in spermatogenesis of golden hamsters. Biol Reprod — PubMed:PMID39239833 | DOI:10.1093/biolre/ioae132 — OMIA Phene_Article / Article
- 2024. Correction to: Single-cell RNA sequencing reveals the important role of Dcaf17 in spermatogenesis of golden hamsters. Biol Reprod — PubMed:PMID39376075 | DOI:10.1093/biolre/ioae144 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:612515 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:241080 (type: trait) — OMIA Group_OMIM (via OMIA_ID)